Journal
GREEN CHEMISTRY
Volume 14, Issue 9, Pages 2484-2490Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2gc35930h
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Funding
- CSIR [01(2433)/10/EMR-II]
- DST, New Delhi [SR/S1/OC-50/2011]
- DST under the DST-IRHPA program
- UGC, New Delhi
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A series of novel highly functionalized 1,4-pyranonaphthoquinones has been synthesized stereoselectively from one-pot sequential reactions of anilines, diethyl acetylenedicarboxylate, 2-hydroxynaphthalene-1,4-dione and benzaldehydes under microwave irradiation. This solvent-and catalyst-free transformation affording biologically relevant heterocycles presumably involves two Michael additions, aldol condensation and annulation reactions.
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