4.8 Article

Preparation of highly chemoselective N-phthaloyl chitosan in aqueous media

Journal

GREEN CHEMISTRY
Volume 13, Issue 6, Pages 1499-1502

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0gc00860e

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Funding

  1. KAKENHI of JSPS [20559003]
  2. Grants-in-Aid for Scientific Research [20559003, 22550197] Funding Source: KAKEN

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Highly chemoselective N-phthaloylations of chitosan were achieved by reaction in aqueous acetic acid media in concentrations from 0 to 10.0%. The degree of substitution (DS) values of phthaloyl groups determined by elemental analysis and H-1 NMR were approximately 1. The H-1 and C-13 NMR spectra strongly support the structural uniformity of N-phthaloyl chitosan.

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