4.8 Article

Solvent-free synthesis of 1,4-disubstituted 1,2,3-triazoles using a low amount of Cu(PPh3)2NO3 complex

Journal

GREEN CHEMISTRY
Volume 12, Issue 12, Pages 2120-2123

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0gc00381f

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Funding

  1. Scientific Research Foundation for the State Education Ministry [107108]
  2. National Science Foundation of P. R. China [J0730425]

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We have developed an environmentally friendly and highly efficient method for copper-catalyzed cycloaddition of organic azides and terminal alkynes under solvent-free conditions. The protocol uses the cheap and easy-to-prepare Cu(PPh3)(2)NO3 complex as the catalyst.

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