Journal
GREEN CHEMISTRY
Volume 12, Issue 12, Pages 2157-2163Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0gc00493f
Keywords
-
Funding
- EPSRC
- Pfizer [EP/G027544/1]
- Engineering and Physical Sciences Research Council [EP/G027544/1] Funding Source: researchfish
- EPSRC [EP/G027544/1] Funding Source: UKRI
Ask authors/readers for more resources
A safe, practical and selective process for the aerobic oxidation of alcohols to aldehydes and ketones has been developed using an Ru catalyst in a continuous flow reactor. Benzylic and allylic alcohols ace oxidised selectively to their corresponding aldehydes and ketones, including substrates containing N- and S-heteroatoms. The rate of turnover is compatible with that previously reported using batch or microchannel reactors under optimised conditions. A preliminary kinetic model is derived that is supported by experimental observations. Last but not least, tandem oxidation-olefination may be achieved without the need to isolate the alcohol intermediate or to switch solvent.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available