Journal
GREEN CHEMISTRY
Volume 12, Issue 6, Pages 949-952Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b926498a
Keywords
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Funding
- National Natural Science Foundation of China [20873179]
- Renmin University of China
- Hong Kong Research Grants Council [PolyU 5001/07P]
- Hong Kong UGC [AoE P/10-01]
- Hong Kong Polytechnic University
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The room temperature ionic liquid [bmim][PF6] has been demonstrated to be an efficient and recyclable medium for highly chemoselective synthesis of 2,2-dimethyl-6-substituted 4-piperidones via a L-proline catalyzed tandem Mannich reaction of ammonia, aldehydes and acetone, and good yields were achieved for aryl and alkyl aldehydes.
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