Journal
GREEN CHEMISTRY
Volume 11, Issue 4, Pages 492-497Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b821842k
Keywords
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Funding
- Industrial Advisory Board of QUILL
- EPSRC [EP/D029538/1]
- Engineering and Physical Sciences Research Council [EP/D029538/1] Funding Source: researchfish
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Microbial biofilms are ubiquitous in nature and represent the predominant mode of growth of microorganisms. A general characteristic of biofilm communities is that they tend to exhibit significant tolerance to antimicrobial challenge compared with planktonic bacteria of the same species The antibiofilm activity of a series of 1-alkyl-3-methylimidazolium chloride ionic liquids has been evaluated against a panel of clinically significant microbial pathogens, including MRSA. A comparison of antimicrobial activity against planktonic bacteria and established biofilms is presented. In general, these ionic liquids possess potent, broad spectrum antibiofilm activity.
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