Journal
GREEN CHEMISTRY
Volume 11, Issue 9, Pages 1465-1476Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b906684e
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Funding
- National Science Foundation of China [20802074]
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In the presence of molecular sieve (MS) 4 angstrom in DMF, a catalyst-free aldol condensation of a variety of aromatic and aliphatic ketones with isatins under mild reaction conditions has been developed. This approach may provide access to a wide range of 3-substituted-3-hydroxyindolin-2-ones in good to excellent yields.
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