Journal
GREEN CHEMISTRY
Volume 10, Issue 9, Pages 995-998Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b807892k
Keywords
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Funding
- University of Minho and Fundacao para a Ciencia e Tecnologia [POCI/QUI/59356/2004]
- [SFRH/BD/31531/2006]
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A series of new 2-imino-2H-chromene-3-carboxamides 5 were synthesized in excellent yield and high atom economy by the Knoevenagel condensation of salicylaldehyde derivatives 4 and N-substituted cyanoacetamides 3 using aqueous sodium carbonate or hydrogen carbonate solution, at room temperature. Treatment of compounds 5 with aqueous HCl led to the formation of the corresponding 2-oxochromenes 6.
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