4.8 Article

One-pot chemoenzymatic syntheses of enantiomerically-enriched O-acetyl cyanohydrins from aldehydes in ionic liquid

Journal

GREEN CHEMISTRY
Volume 10, Issue 3, Pages 283-286

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b717235d

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A practical and efficient method for the synthesis of optically active O-acetyl cyanohydrins via one-pot lipase-catalyzed kinetic resolution of the in situ generated racemic cyanohydrins or O-acetyl cyanohydrins using an ionic liquid as both reaction media and promoter has been described.

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