Journal
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
Volume 252, Issue 8, Pages 1273-1281Publisher
SPRINGER
DOI: 10.1007/s00417-014-2690-7
Keywords
Genetics; CFH; ARMS2; ABCA1; Drusen; Phenotype; Early age-related macular degeneration
Categories
Funding
- Deutsche Forschungsgemeinschaft [HE 2293/5-1, 5-2, 5-3, PA 357/7-1]
- Intramural Fund (IMF) of the Medical Faculty of the University of Munster
- Pro Retina Foundation
- Jackstaedt Foundation
Ask authors/readers for more resources
Genetic factors contribute to the development and progression of age-related macular degeneration (AMD). We aimed to assess the association of drusen as phenotypic characteristics of early AMD and their progression with polymorphisms in the CFH, ABCA1, and ARMS2 genes. In the Munster Aging and Retina Study (MARS), drusen were detected in 406 patients with early AMD and 170 healthy controls according to the International Classification using fundus photographs, with a follow-up examination after 2.6 years (median). Six drusen features were assessed: drusen number (
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
