Journal
GLYCOBIOLOGY
Volume 24, Issue 5, Pages 402-406Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/glycob/cwu018
Keywords
-
Categories
Funding
- Max Planck Society
- Marie Curie grant [PCIG09-GA-2011-293847]
- European Union [278535, 259896]
- Biotechnology and Biological Sciences Research Council [BB/K016164/1, BB/I017011/1]
- Australian Government project NeCTAR
- Education Investment Fund
- NIH/NIGMS [P41GM104603]
- National Center for Glycomics and Glycoproteomics [8P41GM103490]
- Swedish Foundation for International Cooperation in Research and Higher Education
- Wellcome Trust Biomedical Resource grant [WT099197MA]
- BBSRC [BB/K016164/1, BB/I017011/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/I017011/1, BB/K016164/1] Funding Source: researchfish
Ask authors/readers for more resources
The MIRAGE (minimum information required for a glycomics experiment) initiative was founded in Seattle, WA, in November 2011 in order to develop guidelines for reporting the qualitative and quantitative results obtained by diverse types of glycomics analyses, including the conditions and techniques that were applied to prepare the glycans for analysis and generate the primary data along with the tools and parameters that were used to process and annotate this data. These guidelines must address a broad range of issues, as glycomics data are inherently complex and are generated using diverse methods, including mass spectrometry (MS), chromatography, glycan array-binding assays, nuclear magnetic resonance (NMR) and other rapidly developing technologies. The acceptance of these guidelines by scientists conducting research on biological systems in which glycans have a significant role will facilitate the evaluation and reproduction of glycomics experiments and data that is reported in scientific journals and uploaded to glycomics databases. As a first step, MIRAGE guidelines for glycan analysis by MS have been recently published (Kolarich D, Rapp E, Struwe WB, Haslam SM, Zaia J., et al. 2013. The minimum information required for a glycomics experiment (MIRAGE) project - Improving the standards for reporting mass spectrometry-based glycoanalytic data. Mol. Cell Proteomics. 12:991-995), allowing them to be implemented and evaluated in the context of real-world glycobiology research. In this paper, we set out the historical context, organization structure and overarching objectives of the MIRAGE initiative.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available