Journal
GLYCOBIOLOGY
Volume 18, Issue 8, Pages 570-586Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/glycob/cwn041
Keywords
affinity label; glycoside hydrolase; mechanism-based inactivator
Categories
Ask authors/readers for more resources
Glycoside hydrolases are important enzymes in a number of essential biological processes. Irreversible inhibitors of this class of enzyme have attracted interest as probes of both structure and function. In this review we discuss some of the compounds used to covalently modify glycosidases, their use in residue identification, structural and mechanistic investigations, and finally their applications, both in vitro and in vivo, to complex biological systems.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available