Journal
GENETICS AND MOLECULAR RESEARCH
Volume 7, Issue 2, Pages 444-450Publisher
FUNPEC-EDITORA
DOI: 10.4238/vol7-2gmr443
Keywords
Toxocara canis; BALB/c mice; larval recovery; visceral larva migrans; infection
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In the present study, the initial developmental stage of Toxocara canis eggs and larvae, and number of recovered larvae from BALB/c mouse-infected organs are described. In vitro culture of T. canis detects the frequencies of interphasic, mitotic and embryonated eggs only within a 7-day period. Analysis by egg counting was carried out for 32 days. The results showed that at 7 days after cultivation, the frequency of larvae was 50.4% and that this frequency reached 52.8% in 32 days. In the experimental infection of BALB/c mice with T. canis, the number of recovered larvae statistically increased in the brain and liver, with doses of approximately 200 and 1000 eggs. After 7 days of infection, a larger number of larvae were obtained in the lung and liver, although a maximum amount was found in the brain after a 15-or 30-day post-infection period.
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