Journal
GENETICS
Volume 194, Issue 2, Pages 327-334Publisher
GENETICS SOCIETY AMERICA
DOI: 10.1534/genetics.113.150581
Keywords
-
Categories
Funding
- National Institutes of Health [GM061252]
Ask authors/readers for more resources
Meiotic crossovers facilitate the segregation of homologous chromosomes and increase genetic diversity. The formation of meiotic crossovers was previously posited to occur via two pathways, with the relative use of each pathway varying between organisms; however, this paradigm could not explain all crossovers, and many of the key proteins involved were unidentified. Recent studies that identify some of these proteins reinforce and expand the model of two meiotic crossover pathways. The results provide novel insights into the evolutionary origins of the pathways, suggesting that one is similar to a mitotic DNA repair pathway and the other evolved to incorporate special features unique to meiosis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available