Journal
GENETICA
Volume 137, Issue 1, Pages 19-37Publisher
SPRINGER
DOI: 10.1007/s10709-009-9355-1
Keywords
Gene duplication; Population genetics; Selection; Mutation; Adaptive evolution; Theory
Categories
Funding
- Graduate University
- Japan Society for the Promotion of Science
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Various population genetic models of duplicated genes are introduced. The problems covered in this review include the fixation process of a duplicated copy, copy number polymorphism, the fates of duplicated genes and single nucleotide polymorphism in duplicated genes. Because of increasing evidence for concerted evolution by gene conversion, this review introduces recently developed gene conversion models. In the first half, models assuming independent evolution of duplicated genes are introduced, and then the effect of gene conversion is considered in the second half.
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