Journal
GENES & DEVELOPMENT
Volume 26, Issue 7, Pages 631-637Publisher
COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
DOI: 10.1101/gad.190777.112
Keywords
BCFA; branched chain fatty acid; acyl-CoA synthetase; somatic gonad; exocytosis; inositol trisphosphate
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Funding
- National Institutes of Health (USA) [R01-DK074114]
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Animals synthesize a vast range of fatty acids serving diverse cellular functions. The roles of specific fatty acids in early development are just beginning to be characterized. In the March 15, 2012, issue of Genes & Development, Kniazeva and colleagues (pp. 554-566) describe how the particular combination of a branched chain fatty acid and an acyl-CoA synthetase is required for critical cellular processes during early embryogenesis in Caenorhabditis elegans.
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