4.7 Article

A terminator of floral stem cells

Journal

GENES & DEVELOPMENT
Volume 23, Issue 15, Pages 1705-1708

Publisher

COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
DOI: 10.1101/gad.1834409

Keywords

Arabidopsis thaliana; flower development; homeotic control; MADS protein; AGAMOUS; WUSCHEL; stem cell

Funding

  1. Ministry of Agriculture of China [2008ZX08009-001]
  2. Program for the Youth Science and Technology Phosphor Foundation of Shanghai [08QH14003]
  3. Science and Technology Foundation of Shanghai [083391910400]
  4. U. S. Department of Energy [DE-FG02-02ER15332]
  5. Rijk Zwaan
  6. Fudan University
  7. Pennsylvania State University

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Normal flower development requires the termination of stem cell activities in the floral meristem. The floral regulator AGAMOUS (AG) is necessary for this termination and represses the expression of the stem cell determinant WUSCHEL (WUS), but the repression mechanism was not clear. A recent study by Sun and colleagues (pp. 1791-1804) in this issue of Genes & Development has identified a direct target of AG, KNUCKLES (KNU), which encodes a transcriptional repressor of WUS, providing a key missing link in floral meristem determinacy.

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