Related references
Note: Only part of the references are listed.Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA
Suresh Ramakrishna et al.
GENOME RESEARCH (2014)
A guide to genome engineering with programmable nucleases
Hyongbum Kim et al.
NATURE REVIEWS GENETICS (2014)
Surrogate reporter-based enrichment of cells containing RNA-guided Cas9 nuclease-induced mutations
Suresh Ramakrishna et al.
NATURE COMMUNICATIONS (2014)
Nonviral Gene Delivery to Neural Stem Cells with Minicircles by Microporation
Catarina Madeira et al.
BIOMACROMOLECULES (2013)
A modified TALEN-based system for robust generation of knock-out human pluripotent stem cell lines and disease models
Stefan Frank et al.
BMC GENOMICS (2013)
A TALEN Genome-Editing System for Generating Human Stem Cell-Based Disease Models
Qiurong Ding et al.
CELL STEM CELL (2013)
Minicircle DNA electrotransfer for efficient tissue-targeted gene delivery
S. Chabot et al.
GENE THERAPY (2013)
A library of TAL effector nucleases spanning the human genome
Yongsub Kim et al.
NATURE BIOTECHNOLOGY (2013)
Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease
Seung Woo Cho et al.
NATURE BIOTECHNOLOGY (2013)
Knockout mice created by TALEN-mediated gene targeting
Young Hoon Sung et al.
NATURE BIOTECHNOLOGY (2013)
Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells
Maarten Holkers et al.
NUCLEIC ACIDS RESEARCH (2013)
Stability of Zinc Finger Nuclease Protein Is Enhanced by the Proteasome Inhibitor MG132
Suresh Ramakrishna et al.
PLOS ONE (2013)
Magnetic Separation and Antibiotics Selection Enable Enrichment of Cells with ZFN/TALEN-Induced Mutations
Hyojin Kim et al.
PLOS ONE (2013)
Versatile and Efficient Genome Editing in Human Cells by Combining Zinc-Finger Nucleases With Adeno-Associated Viral Vectors
Eva-Maria Haendel et al.
HUMAN GENE THERAPY (2012)
Zinc-finger Nuclease Editing of Human cxcr4 Promotes HIV-1 CD4+ T Cell Resistance and Enrichment
Jinyun Yuan et al.
MOLECULAR THERAPY (2012)
Targeted gene knockout by direct delivery of zinc-finger nuclease proteins
Thomas Gaj et al.
NATURE METHODS (2012)
Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs)
Yong Lei et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Efficient TALEN-mediated gene knockout in livestock
Daniel F. Carlson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease
Jizhong Zou et al.
BLOOD (2011)
Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations
Frank Soldner et al.
CELL (2011)
Creating Designed Zinc-Finger Nucleases with Minimal Cytotoxicity
Sivaprakash Ramalingam et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
New Generation of Plasmid Backbones Devoid of Antibiotic Resistance Marker for Gene Therapy Trials
Gaelle Vandermeulen et al.
MOLECULAR THERAPY (2011)
Minicircle DNA-based Gene Therapy Coupled With Immune Modulation Permits Long-term Expression of α-L-Iduronidase in Mice With Mucopolysaccharidosis Type I
Mark J. Osborn et al.
MOLECULAR THERAPY (2011)
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells
Kosuke Yusa et al.
NATURE (2011)
Targeted integration in rat and mouse embryos with zinc- finger nucleases
Xiaoxia Cui et al.
NATURE BIOTECHNOLOGY (2011)
Genetic engineering of human pluripotent cells using TALE nucleases
Dirk Hockemeyer et al.
NATURE BIOTECHNOLOGY (2011)
Knockout rats generated by embryo microinjection of TALENs
Laurent Tesson et al.
NATURE BIOTECHNOLOGY (2011)
Surrogate reporters for enrichment of cells with nuclease-induced mutations
Hyojin Kim et al.
NATURE METHODS (2011)
Site-specific integration and tailoring of cassette design for sustainable gene transfer
Angelo Lombardo et al.
NATURE METHODS (2011)
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
Tomas Cermak et al.
NUCLEIC ACIDS RESEARCH (2011)
A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity
Claudio Mussolino et al.
NUCLEIC ACIDS RESEARCH (2011)
Heritable Targeted Inactivation of Myostatin Gene in Yellow Catfish (Pelteobagrus fulvidraco) Using Engineered Zinc Finger Nucleases
Zhangji Dong et al.
PLOS ONE (2011)
De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks
Magdy M. Mahfouz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Targeted Genome Editing Across Species Using ZFNs and TALENs
Andrew J. Wood et al.
SCIENCE (2011)
Find and replace: editing human genome in pluripotent stem cells
Huize Pan et al.
PROTEIN & CELL (2011)
The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
Michael R. Lieber
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 79 (2010)
Targeted Genome Modification in Mice Using Zinc-Finger Nucleases
Iara D. Carbery et al.
GENETICS (2010)
Targeting DNA Double-Strand Breaks with TAL Effector Nucleases
Michelle Christian et al.
GENETICS (2010)
Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome
Russell C. DeKelver et al.
GENOME RESEARCH (2010)
A robust system for production of minicircle DNA vectors
Mark A. Kay et al.
NATURE BIOTECHNOLOGY (2010)
Transient cold shock enhances zinc-finger nuclease-mediated gene disruption
Yannick Doyon et al.
NATURE METHODS (2010)
A nonviral minicircle vector for deriving human iPS cells
Fangjun Jia et al.
NATURE METHODS (2010)
Genome editing with engineered zinc finger nucleases
Fyodor D. Urnov et al.
NATURE REVIEWS GENETICS (2010)
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
Mary Ellen Moynahan et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Gene Targeting of a Disease-Related Gene in Human Induced Pluripotent Stem and Embryonic Stem Cells
Jizhong Zou et al.
CELL STEM CELL (2009)
Novel Minicircle Vector for Gene Therapy in Murine Myocardial Infarction
Mei Huang et al.
CIRCULATION (2009)
Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly
Hye Joo Kim et al.
GENOME RESEARCH (2009)
Precise genome modification in the crop species Zea mays using zinc-finger nucleases
Vipula K. Shukla et al.
NATURE (2009)
Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases
Aron M. Geurts et al.
SCIENCE (2009)
Attenuation of Zinc Finger Nuclease Toxicity by Small-Molecule Regulation of Protein Levels
Shondra M. Pruett-Miller et al.
PLOS GENETICS (2009)
Efficient expression of vascular endothelial growth factor using minicircle DNA for angiogenic gene therapy
Chien-Wen Chang et al.
JOURNAL OF CONTROLLED RELEASE (2008)
Minicircle-DNA production by site specific recombination and protein-DNA interaction chromatography
Peter Mayrhofer et al.
JOURNAL OF GENE MEDICINE (2008)
Rapid Open-Source engineering of customized zinc-finger nucleases for highly efficient gene modification
Morgan L. Maeder et al.
MOLECULAR CELL (2008)
Comparison of zinc finger nucleases for use in gene targeting in mammalian cells
Shondra M. Pruett-Miller et al.
MOLECULAR THERAPY (2008)
CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression
Stephen C. Hyde et al.
NATURE BIOTECHNOLOGY (2008)
Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases
Elena E. Perez et al.
NATURE BIOTECHNOLOGY (2008)
Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases
Yannick Doyon et al.
NATURE BIOTECHNOLOGY (2008)
Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery
Angelo Lombardo et al.
NATURE BIOTECHNOLOGY (2007)
Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases
Michal Szczepek et al.
NATURE BIOTECHNOLOGY (2007)
Histone modifications are associated with the persistence or silencing of vector-mediated transgene expression in vivo
Efren Riu et al.
MOLECULAR THERAPY (2007)
An improved zinc-finger nuclease architecture for highly specific genome editing
Jeffrey C. Miller et al.
NATURE BIOTECHNOLOGY (2007)
High-frequency homologous recombination in plants mediated by zinc-finger nucleases
DA Wright et al.
PLANT JOURNAL (2005)
Highly efficient endogenous human gene correction using designed zinc-finger nucleases
FD Urnov et al.
NATURE (2005)
Targeted mutagenesis using zinc-finger nucleases in Arabidopsis
A Lloyd et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo
ZY Chen et al.
MOLECULAR THERAPY (2003)
Enhancing gene targeting with designed zinc finger nucleases
M Bibikova et al.
SCIENCE (2003)
Chimeric nucleases stimulate gene targeting in human cells
MH Porteus et al.
SCIENCE (2003)
Progress and problems with the use of viral vectors for gene therapy
CE Thomas et al.
NATURE REVIEWS GENETICS (2003)
Stimulation of homologous recombination through targeted cleavage by chimeric nucleases
M Bibikova et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
A Toll-like receptor recognizes bacterial DNA
H Hemmi et al.
NATURE (2000)
Share Paper
