Journal
GENE EXPRESSION PATTERNS
Volume 8, Issue 5, Pages 349-356Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.gep.2008.01.004
Keywords
cadherin; Ciona; development; gene expression; genome; whole mount in situ hybridization
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We have carried out a comprehensive survey of the spatiotemporal expression of cadherin superfamily genes in the basal chordate Ciona intestinalis, as an example of a genome-wide expression study of a gene family directly regulating cellular processes in morphogenesis. We found 15 definitely expressed cadherin superfamily genes in the Ciona intestinalis genome. Up to the late gastrula stage, all identified delta-protocadherins and the type II classical cadherin, but not other subfamily members, were zygotically expressed. At later stages, however, all cadherin superfamily genes were expressed in the nervous system. These data are useful for understanding the role of these genes in Ciona development and the evolution of chordates. (c) 2008 Elsevier B.V. All rights reserved.
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