4.6 Article

Analysis of CYP21A1P and the duplicated CYP21A2 genes

Journal

GENE
Volume 506, Issue 1, Pages 261-262

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.gene.2012.06.045

Keywords

CYP21A1P pseudogene; Duplicated CYP21A2

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The RCCX module on chromosome 6p21.3 has 3 possible forms: monomodular, bimodular, and trimodular. Chromosomes with 4 RCCX modules are very rare. In the monomodule, most of the CYP21A1P genes do not exist. However, haplotypes of the RCCX module with more than one CYP21A2 gene were observed. Obviously, the gene located downstream of the XA gene can possibly include the CYP21A2 as well as the CYP21A1P gene. Crown Copyright (C) 2012 Published by Elsevier B.V. All rights reserved.

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