Journal
GASTROENTEROLOGY CLINICS OF NORTH AMERICA
Volume 42, Issue 2, Pages 299-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.gtc.2013.02.001
Keywords
Gastric Cancer; Chemoprevention; NSAIDs; Helicobacter pylori eradication
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Chemoprevention may form the cornerstone in the management of gastric adenocarcinoma of the future. Helicobacter pylori eradication and aspirin and/or nonsteroidal anti-inflammatory drug therapy have emerged as front-runner chemotherapeutic agents due to the putative pathogenic mechanisms that they address. Before a population-based chemopreventive strategy can be recommended on a large scale, randomized controlled trials with follow-up of more than 10 years of these 2 agents in populations at high gastric adenocarcinoma risk is urgently awaited.
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