Journal
GASTROENTEROLOGY CLINICS OF NORTH AMERICA
Volume 39, Issue 3, Pages 629-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.gtc.2010.08.004
Keywords
Drug-induced diarrhea; Neutropenic enterocolitis; Graft-versus-host disease; Chemotherapy-induced nausea and vomiting; Liver injury
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A spectrum of oncologic treatments including chemotherapy, radiotherapy and molecular targeted therapies is available to combat cancer These treatments are associated with adverse effects in several organ systems including the gastrointestinal (GI) tract The immunocompromised state induced by oncologic therapy is also an important contributing factor underlying GI complications This review discusses common GI complications that can result from cancer therapy The pathologic mechanisms underlying each complication and the pharmacology of the agents used to treat these complications are discussed
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