Journal
GASTROENTEROLOGY
Volume 142, Issue 6, Pages 1360-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1053/j.gastro.2012.01.044
Keywords
Antiviral Therapy; Efficacy; Interferon; Nucleos(t)ide Analogues; Screening
Categories
Funding
- Bristol-Myers Squibb
- Gilead
- GlaxoSmithKline
- Merck
- Roche
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It is important to examine the effectiveness of current therapies for chronic hepatitis B in clinical practice, given the therapeutic advances over the past 15 years. A 2010 Institute of Medicine report on hepatitis and liver cancer stated that the public and health care providers have a lack of knowledge and awareness about viral hepatitis, and that there is a gap between medical innovation and community care. We review the efficacy of hepatitis B treatment, based on results from clinical trials, and discuss the effectiveness of these treatments in clinical practice. We also discuss why having efficacious treatments alone would have a small impact on the global health burden of hepatitis B, and highlight the importance of educating the public and the medical community and coordination of care.
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