Journal
FUTURE VIROLOGY
Volume 3, Issue 3, Pages 243-251Publisher
FUTURE MEDICINE LTD
DOI: 10.2217/17460794.3.3.243
Keywords
antiviral therapeutics; arenavirus; hemorrhagic fever; kinase inhibitors; virology
Categories
Funding
- NIAID NIH HHS [T32 AI007536-01, U01 AI054827, T32 AI007536] Funding Source: Medline
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Arenaviruses are rodent-borne RNA viruses, and some have the capacity to cause hemorrhagic fever and death in infected individuals and thus have been identified as a potential bioterrorism threat. Ribavirin and supportive care are currently the approved therapeutic options for individuals suffering from arenavirus-induced hemorrhagic fever. However, new research has suggested that immune plasma treatment or kinase inhibitors may provide a therapeutic option for treating arenavirus infections in humans. This article puts forth a perspective as to the potential use of kinase inhibitors as an antiviral therapeutic for arenavirus infections.
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