Journal
FUTURE ONCOLOGY
Volume 10, Issue 4, Pages 647-654Publisher
FUTURE MEDICINE LTD
DOI: 10.2217/FON.13.228
Keywords
artemisinin; cancer; cervix; DHA; dysplasia
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Cervical cancer and HPV-related diseases remain a burden in the developing world. While much progress has been gained in the detection of HPV and preneoplastic cervical lesions, the rate-limiting step in the prevention of cervical cancer is management of these women. A natural compound, artemisinin, and its derivatives appear to hold promise as a simple means of treatment. Laboratory studies have shown that this compound, and its derivatives, have activity against HPV-infected and -transformed cells and cervical cancer cells. In situations of compassionate use, studies have also demonstrated efficacy in clinical situations. Well-designed clinical trials relating to its use should be undertaken.
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