4.3 Review

Biofilm-associated infections: antibiotic resistance and novel therapeutic strategies

Journal

FUTURE MICROBIOLOGY
Volume 8, Issue 7, Pages 877-886

Publisher

FUTURE MEDICINE LTD
DOI: 10.2217/fmb.13.58

Keywords

antibiotic resistance; biofilm; infection; treatment

Categories

Funding

  1. National Natural Science Foundation of China [31170127, 81201246]
  2. Military Medical and Technology Twelfth Five-Year Science and Research Key Program [BWS11C073]
  3. Beijing Nova Program [Z121102002512049]

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Infections with bacterial or fungal biofilms have emerged as a major public heath concern because biofilm-growing cells are highly resistant to both antibiotics and host immune defenses. This review focuses on the progress in understanding the mechanisms of biofilm-specific antimicrobial resistance and in developing innovative therapeutic measures based on novel antibiofilm agents.

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