Related references
Note: Only part of the references are listed.Insights into the Role of Heme in the Mechanism of Action of Antimalarials
Jill M. Combrinck et al.
ACS CHEMICAL BIOLOGY (2013)
Iron(III) Protoporphyrin IX Complexes of the Antimalarial Cinchona Alkaloids Quinine and Quinidine
Katherine A. de Villiers et al.
ACS CHEMICAL BIOLOGY (2012)
High content live cell imaging for the discovery of new antimalarial marine natural products
Serena Cervantes et al.
BMC INFECTIOUS DISEASES (2012)
Application of NMR Metabolomics to Search for Human Disease Biomarkers
Teklab Gebregiworgis et al.
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2012)
Direct Tests of Enzymatic Heme Degradation by the Malaria Parasite Plasmodium falciparum
Paul A. Sigala et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Oriented nucleation of hemozoin at the digestive vacuole membrane in Plasmodium falciparum
Sergey Kapishnikov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
PfCRT and its role in antimalarial drug resistance
Andrea Ecker et al.
TRENDS IN PARASITOLOGY (2012)
Use of the NP-40 Detergent-Mediated Assay in Discovery of Inhibitors of β-Hematin Crystallization
Rebecca D. Sandlin et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2011)
Structure and Formation of Synthetic Hemozoin: Insights From First-Principles Calculations
Noa Marom et al.
CRYSTAL GROWTH & DESIGN (2011)
The Plasmodium falciparum-infected red blood cell
Leann Tilley et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2011)
On the mechanisms involved in biological heme crystallization
Renata Stiebler et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2011)
Investigating the Antimalarial Action of 1,2,4-Trioxolanes with Fluorescent Chemical Probes
Carmony L. Hartwig et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria
Jane Achan et al.
MALARIA JOURNAL (2011)
Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion
Nectarios Klonis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Hematin-Hematin Self-Association States Involved in the Formation and Reactivity of the Malaria Parasite Pigment, Hemozoin
Nectarios Klonis et al.
BIOCHEMISTRY (2010)
The Neutral Lipid Composition Present in the Digestive Vacuole of Plasmodium falciparum Concentrates Heme and Mediates β-Hematin Formation with an Unusually Low Activation Energy
Anh N. Hoang et al.
BIOCHEMISTRY (2010)
Lipophilic Mediated Assays for β-Hematin Inhibitors
Melissa D. Carter et al.
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2010)
Crystallization of synthetic haemozoin (beta-haematin) nucleated at the surface of lipid particles
Anh N. Hoang et al.
DALTON TRANSACTIONS (2010)
Thousands of chemical starting points for antimalarial lead identification
Francisco-Javier Gamo et al.
NATURE (2010)
Colorimetric High-Throughput Screen for Detection of Heme Crystallization Inhibitors
Margaret A. Rush et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Accumulation of artemisinin trioxane derivatives within neutral lipids of Plasmodium falciparum malaria parasites is endoperoxide-dependent
Carmony L. Hartwig et al.
BIOCHEMICAL PHARMACOLOGY (2009)
High-content live cell imaging with RNA probes: advancements in high-throughput antimalarial drug discovery
Serena Cervantes et al.
BMC CELL BIOLOGY (2009)
Host-Parasite Interactions Revealed by Plasmodium falciparum Metabolomics
Kellen L. Olszewski et al.
CELL HOST & MICROBE (2009)
Disruption of a Plasmodium falciparum Multidrug Resistance-associated Protein (PfMRP) Alters Its Fitness and Transport of Antimalarial Drugs and Glutathione
Dipak Kumar Raj et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Autofluorescence of Condensed Heme Aggregates in Malaria Pigment and Its Synthetic Equivalent Hematin Anhydride (β-Hematin)
Marie-Josee Bellemare et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2009)
Chloroquine Transport via the Malaria Parasite's Chloroquine Resistance Transporter
Rowena E. Martin et al.
SCIENCE (2009)
Malaria and poverty
Awash Teklehaimanot et al.
REDUCING THE IMPACT OF POVERTY ON HEALTH AND HUMAN DEVELOPMENT: SCIENTIFIC APPROACHES (2008)
Interplay Between Malaria, Crystalline Hemozoin Formation, and Antimalarial Drug Action and Design
Isabelle Weissbuch et al.
CHEMICAL REVIEWS (2008)
The crystal structure of halofantrine-ferriprotoporphyrin IX and the mechanism of action of arylmethanol antimalarials
Katherine A. de Villiers et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2008)
Haemozoin formation
Timothy J. Egan
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2008)
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen
David Plouffe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
HDP - A novel heme detoxification protein from the malaria parasite
Dewal Jani et al.
PLOS PATHOGENS (2008)
A non-radiolabeled heme-GSH interaction test for the screening of antimalarial compounds
Glovanny Garavito et al.
EXPERIMENTAL PARASITOLOGY (2007)
Assessment and continued validation of the malaria SYBR green I-based fluorescence assay for use in malaria drug screening
Jacob D. Johnson et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2007)
Differences in trans-stimulated chloroquine efflux kinetics are linked to PfCRT in Plasmodium falciparum
Cecilia P. Sanchez et al.
MOLECULAR MICROBIOLOGY (2007)
Crystal nucleation, growth, and morphology of the synthetic malaria pigment β-hematin and the effect thereon by quinoline additives:: The malaria pigment as a target of various antimalarial drugs
Inna Solomonov et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
The role of neutral lipid nanospheres in Plasmodium falciparum haem crystallization
John M. Pisciotta et al.
BIOCHEMICAL JOURNAL (2007)
Simple colorimetric inhibition assay of heme crystallization for high-throughput screening of antimalarial compounds
Nguyen Tien Huy et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2007)
The silent path to thousands of merozoites:: the Plasmodium liver stage
Miguel Prudencio et al.
NATURE REVIEWS MICROBIOLOGY (2006)
The basis of the immunomodulatory activity of malaria pigment (hemozoin)
Clare K. Carney et al.
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2006)
Haemozoin (β-haematin) biomineralization occurs by self-assembly near the lipid/water interface
Timothy J. Egan et al.
FEBS LETTERS (2006)
Reflections on the 'discovery' of the antimalarial qinghao
Elisabeth Hsu
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2006)
Plasmodium falciparum:: Stage specific effects of a selective inhibitor of lactate dehydrogenase
L Vivas et al.
EXPERIMENTAL PARASITOLOGY (2005)
Quinoline antimalarials decrease the rate of β-hematin formation
TJ Egan et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2005)
Target-based drug discovery: is something wrong?
F Sams-Dodd
DRUG DISCOVERY TODAY (2005)
Xanthones as antimalarial agents: Discovery, mode of action, and optimization
M Riscoe et al.
CURRENT MEDICINAL CHEMISTRY (2005)
Structure of the amodiaquine-FPIX μ oxo dimer solution complex at atomic resolution
AC de Dios et al.
INORGANIC CHEMISTRY (2004)
Antimalarial quinolines and artemisinin inhibit endocytosis in Plasmodium falciparum
HC Hoppe et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)
Inhibition of heme crystal growth by antimalarials and other compounds: implications for drug discovery
CR Chong et al.
BIOCHEMICAL PHARMACOLOGY (2003)
Hemozoin formation in malaria: a two-step process involving histidine-rich proteins and lipids
AV Pandey et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
NMR studies of chloroquine-ferriprotoporphyrin IX complex
AC de Dios et al.
JOURNAL OF PHYSICAL CHEMISTRY A (2003)
Artemisinin antimalarials do not inhibit hemozoin formation
RK Haynes et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2003)
Plasmodium falciparum: sacrificing membrane to grow crystals?
E Hempelmann et al.
TRENDS IN PARASITOLOGY (2003)
Quinoline binding site on malaria pigment crystal:: A rational pathway for antimalaria drug design
R Buller et al.
CRYSTAL GROWTH & DESIGN (2002)
Plasmodium sporozoite invasion into insect and mammalian cells is directed by the same dual binding system
K Matuschewski et al.
EMBO JOURNAL (2002)
Epidemiology of drug-resistant malaria
C Wongsrichanalai et al.
LANCET INFECTIOUS DISEASES (2002)
Optimization of xanthones for antimalarial activity: the 3,6-bis-omega-diethylaminoalkoxyxanthone series
JX Kelly et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2002)
A spectroscopic investigation of the binding interactions between 4,5-dihydroxyxanthone and heme
JX Kelly et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2001)
Phagocytosis of malarial pigment haemozoin by human monocytes: a confocal microscopy study
E Schwarzer et al.
PARASITOLOGY (2001)
Hematin polymerization assay as a high-throughput screen for identification of new antimalarial pharmacophores
Y Kurosawa et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2000)
Share Paper
