Journal
FUNGAL GENETICS AND BIOLOGY
Volume 49, Issue 9, Pages 677-678Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.fgb.2012.01.008
Keywords
Candida albicans; Macrophage; Phagocytosis; Innate immunology; Fungal infection
Categories
Funding
- Chief Scientist Office [SCD/03]
- Wellcome Trust [089930, 080088, 075470]
- [HEALTH-F2-2010-260338-ALL-FUN]
- Chief Scientist Office [SCD/03] Funding Source: researchfish
Ask authors/readers for more resources
Candida albicans is an opportunistic pathogen and is recognised and phagocytosed by macrophages. Using live-cell imaging, non-lytic expulsion/exocytosis of C. albicans from macrophages is demonstrated for the first time. Following complete expulsion, both the phagocyte and pathogen remain intact and viable. Partial engulfment of hyphal C albicans without macrophage lysis is also demonstrated. These observations underpin the complexity of interactions between C. albicans and innate immune cells. (C) 2012 Elsevier Inc. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
