Related references
Note: Only part of the references are listed.Hydroxylation of methylated CpG dinucleotides reverses stabilisation of DNA duplexes by cytosine 5-methylation
Armin Thalhammer et al.
CHEMICAL COMMUNICATIONS (2011)
Hypothesis Environmental regulation of 5-hydroxymethyl-cytosine by oxidative stress
Nancy Chia et al.
EPIGENETICS (2011)
Molecular mechanisms of pesticide-induced neurotoxicity: Relevance to Parkinson's disease
Rodrigo Franco et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2010)
Methylation Regulates Alpha-Synuclein Expression and Is Decreased in Parkinson's Disease Patients' Brains
Ahmad Jowaed et al.
JOURNAL OF NEUROSCIENCE (2010)
Degeneration of dopaminergic neurons induced by thrombin injection in the substantia nigra of the rat is enhanced by dexamethasone: Role of monoamine oxidase enzyme
Sandro Argueelles et al.
NEUROTOXICOLOGY (2010)
CpG Demethylation Enhances Alpha-Synuclein Expression and Affects the Pathogenesis of Parkinson's Disease
Lumine Matsumoto et al.
PLOS ONE (2010)
SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis
Ruth Luthi-Carter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Essential Role of the Histone Methyltransferase G9a in Cocaine-Induced Plasticity
Ian Maze et al.
SCIENCE (2010)
Cell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps
Oren A. Levy et al.
APOPTOSIS (2009)
The epigenetic effects of amyloid-β1-40 on global DNA and neprilysin genes in murine cerebral endothelial cells
Un-Lin Chen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
PDbase: a database of Parkinson's Disease-related genes and genetic variation using substantia nigra ESTs
Jin Ok Yang et al.
BMC GENOMICS (2009)
Trans-2-phenylcyclopropylamine induces nerve cells apoptosis in zebrafish mediated by depression of LSD1 activity
Zhang Jie et al.
BRAIN RESEARCH BULLETIN (2009)
LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in Breast Cancer
Yan Wang et al.
CELL (2009)
A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death
Kaoru Saijo et al.
CELL (2009)
Glutamate Receptors as Therapeutic Targets for Parkinson's Disease
Kari A. Johnson et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2009)
Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression
Frank M. J. Jacobs et al.
DEVELOPMENT (2009)
Neprilysin gene expression requires binding of the amyloid precursor protein intracellular domain to its promoter: implications for Alzheimer disease
Nikolai D. Belyaev et al.
EMBO REPORTS (2009)
LSD1 demethylates histone and non-histone proteins
Thomas B. Nicholson et al.
EPIGENETICS (2009)
Molecular pathogenesis of Parkinson disease: insights from genetic studies
Thomas Gasser
EXPERT REVIEWS IN MOLECULAR MEDICINE (2009)
Parkinson's disease: from monogenic forms to genetic susceptibility factors
Suzanne Lesage et al.
HUMAN MOLECULAR GENETICS (2009)
Histone H2A ubiquitination in transcriptional regulation and DNA damage repair
Wenlai Zhou et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)
A Sporadic Parkinson Disease Model via Silencing of the Ubiquitin-Proteasome/E3 Ligase Component SKP1A
Tali Fishman-Jacob et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
DNA Methylation of Alzheimer Disease and Tauopathy-Related Genes in Postmortem Brain
Marta Barrachina et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2009)
Genetics, environmental factors and the emerging role of epigenetics in neurodegenerative diseases
Lucia Migliore et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2009)
HDAC2 negatively regulates memory formation and synaptic plasticity
Ji-Song Guan et al.
NATURE (2009)
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
Michael Haberland et al.
NATURE REVIEWS GENETICS (2009)
Brain-derived neurotrophic factor in neurodegenerative diseases
Chiara Zuccato et al.
NATURE REVIEWS NEUROLOGY (2009)
Genomic and proteomic biomarkers for Parkinson disease
Thomas Gasser
NEUROLOGY (2009)
Regulation of Neuronal Survival Factor MEF2D by Chaperone-Mediated Autophagy
Qian Yang et al.
SCIENCE (2009)
Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
Mamta Tahiliani et al.
SCIENCE (2009)
The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain
Skirmantas Kriaucionis et al.
SCIENCE (2009)
Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25 Å
Shinya Mimasu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Inhibition of transcriptional activity of c-JUN by SIRT1
Zhanguo Gao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Facile synthesis of substituted trans-2-arylcyclopropylamine inhibitors of the human histone demethylase LSD1 and monoamine oxidases A and B
David M. Gooden et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
DNA Cytosine Demethylation: Are We Getting Close?
Josef Jiricny et al.
CELL (2008)
On the Pathogenesis and Neuroprotective Treatment of Parkinson Disease: What have we Learned from the Genetic Forms of this Disease?
M. A. Mena et al.
CURRENT MEDICINAL CHEMISTRY (2008)
Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders
Ted Abe et al.
CURRENT OPINION IN PHARMACOLOGY (2008)
Histone deacetylases 1 and 2 are expressed at distinct stages of neuro-glial development
Jessica L. MacDonald et al.
DEVELOPMENTAL DYNAMICS (2008)
Epigenetic analysis reveals a euchromatic configuration in the FMR1 unmethylated full mutations
Elisabetta Tabolacci et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2008)
Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
Paul A. C. Cloos et al.
GENES & DEVELOPMENT (2008)
Parkin Regulates Eg5 Expression by Hsp70 Ubiquitination-dependent Inactivation of c-Jun NH2-terminal Kinase
Min Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Striatal histone modifications in models of levodopa-induced dyskinesia
A. P. Nicholas et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Parkinson's disease: clinical features and diagnosis
J. Jankovic
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2008)
Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (pb): Evidence for a developmental origin and environmental link for AD
Jinfang Wu et al.
JOURNAL OF NEUROSCIENCE (2008)
Decreased NURR1 gene expression in patients with Parkinson's disease
Weidong Le et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2008)
P53-targeted LSD1 functions in repression of chromatin structure and transcription in vivo
Wen-Wei Tsai et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
SIRT1 and neuronal diseases
Bor Luen Tang et al.
MOLECULAR ASPECTS OF MEDICINE (2008)
Different methylation of the TNF-alpha promoter in cortex and substantia nigra: Implications for selective neuronal vulnerability
Heike C. Pieper et al.
NEUROBIOLOGY OF DISEASE (2008)
Age-Specific Epigenetic Drift in Late-Onset Alzheimer's Disease
Sun-Chong Wang et al.
PLOS ONE (2008)
Epigenetic and pharmacoepigenomic studies of major psychoses and potentials for therapeutics
Hamid Mostafavi Abdolmaleky et al.
PHARMACOGENOMICS (2008)
Epigenetic mechanisms in drug addiction
William Renthal et al.
TRENDS IN MOLECULAR MEDICINE (2008)
Synphilin-1 isoforms in Parkinson's disease: regulation by phosphorylation and ubiquitylation
R. Szargel et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
Concepts in sumoylation: a decade on
Ruth Geiss-Friedlander et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers
Sean D. Taverna et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
DNA methylation: The nuts and bolts of repression
Tina Branscombe Miranda et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2007)
Cross-regulation of histone modifications
John A. Latham et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Regulation of cell cycle progression and gene expression by H2A deubiquitination
Heui-Yun Joo et al.
NATURE (2007)
Prefrontal dysfunction in schizophrenia involves mixed-lineage leukemia 1-regulated histone methylation at GABAergic gene promoters
Hsien-Sung Huang et al.
JOURNAL OF NEUROSCIENCE (2007)
Are Parkinson disease patients protected from some but not all cancers?
Rivka Inzelberg et al.
NEUROLOGY (2007)
Casein kinase 2 is the major enzyme in brain that phosphorylates Ser129 of human α-synuclein:: Implication for α-synucleinopathies
Aasami Ishii et al.
FEBS LETTERS (2007)
DNA Methylation in the Human Cerebral Cortex Is Dynamically Regulated throughout the Life Span and Involves Differentiated Neurons
Kimberly D. Siegmund et al.
PLOS ONE (2007)
p53 is regulated by the lysine demethylase LSD1
Jing Huang et al.
NATURE (2007)
The F-box protein Fbl10 is a novel transcriptional repressor of c-Jun
Ryo Koyama-Nasu et al.
NATURE CELL BIOLOGY (2007)
GAD1 mRNA Expression and DNA Methylation in Prefrontal Cortex of Subjects with Schizophrenia
Hsien-Sung Huang et al.
PLOS ONE (2007)
Sirtuin 2 inhibitors rescue α-synuclein-mediated toxicity in models of Parkinson's disease
Tiago Fleming Outeiro et al.
SCIENCE (2007)
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
Dohoon Kim et al.
EMBO JOURNAL (2007)
Pharmacological inhibition of PARP-1 reduces α-synucleinand MPP+-induced cytotoxicity in Parkinson's disease in vitro models
Tiago Fleming Outeiro et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
The lysine-specific demethylase 1 is required for cell proliferation in both p53-dependent and -independent manners
Ariane Scoumanne et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Modulation of nucleosome dynamics in Huntington's disease
Edward C. Stack et al.
HUMAN MOLECULAR GENETICS (2007)
Recovery of learning and memory is associated with chromatin remodelling
Andre Fischer et al.
NATURE (2007)
Genetic heterogeneity in Rubinstein-Taybi syndrome:: delineation of the phenotype of the first patients carrying mutations in EP300
Deborah Bartholdi et al.
JOURNAL OF MEDICAL GENETICS (2007)
P53 protein, interferon-γ, and NF-κB levels are elevated in the parkinsonian brain
Makio Mogi et al.
NEUROSCIENCE LETTERS (2007)
Chromatin modifications and their function
Tony Kouzarides
CELL (2007)
Dynamic regulation of histone lysine methylation by demethylases
Yang Shi et al.
MOLECULAR CELL (2007)
Gene and protein signatures in sporadic Parkinson's disease and a novel genetic model of PD
Silvia A. Mandel et al.
PARKINSONISM & RELATED DISORDERS (2007)
Regulation of histone methylation by demethylimination and demethylation
Robert J. Klose et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
p53 mediates nontranscriptional cell death in dopaminergic cells in response to proteasome inhibition
Venugopalan D. Nair et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
CTIP2 associates with the NuRD complex on the promoter of p57KIP2, a newly identified CTIP2 target gene
Acharawan Topark-Ngarm et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
α-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity
Eirene Kontopoulos et al.
HUMAN MOLECULAR GENETICS (2006)
The role of CDK5/P25 formation/inhibition in neurodegeneration
Antoni Camins et al.
DRUG NEWS & PERSPECTIVES (2006)
Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets
Micah D. Gearhart et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Endogenous α-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity
Yan Leng et al.
JOURNAL OF NEUROSCIENCE (2006)
Abnormal Sp1 transcription factor expression in Alzheimer disease and tauopathies
G Santpere et al.
NEUROSCIENCE LETTERS (2006)
Control of MEF2 transcriptional activity by coordinated phosphorylation and sumoylation
S Gregoire et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Calpain-regulated p35/cdk5 plays a central role in dopaminergic neuron death through modulation of the transcription factor myocyte enhancer factor 2
PD Smith et al.
JOURNAL OF NEUROSCIENCE (2006)
Human histone demethylase LSD1 reads the histone code
F Forneris et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Inhibition of Aurora-B kinase activity by poly(ADP-ribosyl)ation in response to DNA damage
L Monaco et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Regulation of MEF2 by histone deacetylase 4-and SIRT1 deacetylase-mediated lysine modifications
X Zhao et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
E Michishita et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Regulation of LSD1 histone demethylase activity by its associated factors
YJ Shi et al.
MOLECULAR CELL (2005)
Neurodegenerative disorders: Parkinson's disease and Huntington's disease
SM Hague et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2005)
Cyclin-dependent kinase 5 mediates neurotoxin-induced degradation of the transcription factor myocyte enhancer factor 2
XL Tang et al.
JOURNAL OF NEUROSCIENCE (2005)
Differential epigenetic modifications in the FMR1 gene of the fragile X syndrome after reactivating pharmacological treatments
E Tabolacci et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2005)
Phosphorylation of histone H4 serine 1 during DNA damage requires casein kinase II in S-cerevisiae
WL Cheung et al.
CURRENT BIOLOGY (2005)
Genetic heterogeneity in Rubinstein-Taybi syndrome:: Mutations in both the CBP and EP300 genes cause disease
JH Roelfsema et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2005)
The role of Nurr1 in the development of dopaminergic neurons and Parkinson's disease
J Jankovic et al.
PROGRESS IN NEUROBIOLOGY (2005)
Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease
G Gardian et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration
CA Saura et al.
NEURON (2004)
Decreased cAMP response element-mediated transcription - An early event in exon 1 and full-length cell models of Huntington's disease that contributes to polyglutamine pathogenesis
KL Sugars et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Opening the chromatin for transcription
YJ Li et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Histone demethylation mediated by the nuclear arnine oxidase homolog LSD1
YJ Shi et al.
CELL (2004)
Molecular pathways to neurodegeneration
E Bossy-Wetzel et al.
NATURE MEDICINE (2004)
Chemotherapy for the brain: The antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease
RJ Ferrante et al.
JOURNAL OF NEUROSCIENCE (2004)
Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice:: A model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration
JM Alarcón et al.
NEURON (2004)
CBP histone acetyltransferase activity is a critical component of memory consolidation
E Korzus et al.
NEURON (2004)
Protein kinase CK2 is an inhibitor of the neuronal Cdk5 kinase
ACB Lim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase
F Yeung et al.
EMBO JOURNAL (2004)
Transcriptome analysis in a rat model of L-DOPA-induced dyskinesia
C Konradi et al.
NEUROBIOLOGY OF DISEASE (2004)
Neuroprotective effects of phenylbutyrate against MPTP neurotoxicity
G Gardian et al.
NEUROMOLECULAR MEDICINE (2004)
BDNF is induced by wild-type α-synuclein but not by the two mutants, A30P or A53T, in glioma cell line
R Kohno et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
p57Kip2 cooperates with Nurr1 in developing dopamine cells
B Joseph et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Critical loss of CBP/p300 histone acetylase activity by caspase-6 during neurodegeneration
C Rouaux et al.
EMBO JOURNAL (2003)
DNA methylation-related chromatin remodeling in activity-dependent Bdnf gene regulation
K Martinowich et al.
SCIENCE (2003)
Class II histone deacetylases: versatile regulators
E Verdin et al.
TRENDS IN GENETICS (2003)
Presenilin 1 gene silencing by S-adenosylmethionine:: a treatment for Alzheimer disease?
S Scarpa et al.
FEBS LETTERS (2003)
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease
E Hockly et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Oxidative stress in Parkinson's disease
P Jenner
ANNALS OF NEUROLOGY (2003)
Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3
MD Shahbazian et al.
NEURON (2002)
On the epigenetic regulation of the human reelin promoter
Y Chen et al.
NUCLEIC ACIDS RESEARCH (2002)
A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes
MA Hakimi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Decreased expression of the transcription factor NURR1 in dopamine neurons of cocaine abusers
MJ Bannon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Histone modifications in transcriptional regulation
SL Berger
CURRENT OPINION IN GENETICS & DEVELOPMENT (2002)
Comprehensive analysis of CpG islands in human chromosomes 21 and 22
D Takai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Cooperation between complexes that regulate chromatin structure and transcription
GJ Narlikar et al.
CELL (2002)
The human dopamine transporter gene: gene organization, transcriptional regulation, and potential involvement in neuropsychiatric disorders
MJ Bannon et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2001)
Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
JS Steffan et al.
NATURE (2001)
A transcriptively active complex of APP with Fe65 and histone acetyltransferase Tip60
XW Cao et al.
SCIENCE (2001)
Histone deacetylase complexes: functional entities or molecular reservoirs
S Khochbin et al.
FEBS LETTERS (2001)
α-synuclein forms a complex with transcription factor Elk-1
A Iwata et al.
JOURNAL OF NEUROCHEMISTRY (2001)
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
J Guy et al.
NATURE GENETICS (2001)
Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
RZ Chen et al.
NATURE GENETICS (2001)
Acetylation of histones and transcription-related factors
DE Sterner et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2000)
Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease:: Implications for pathogenesis and therapy
KA Conway et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
The language of covalent histone modifications
BD Strahl et al.
NATURE (2000)
Cell death mechanisms in Parkinson's disease
KA Jellinger
JOURNAL OF NEURAL TRANSMISSION (2000)