Journal
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
Volume 13, Issue -, Pages S40-S46Publisher
WILEY
DOI: 10.1111/jth.12976
Keywords
angiogenesis stimulators; cancer; inflammation; cell-derived microparticles; platelets
Categories
Ask authors/readers for more resources
Platelets are known to play a central role in primary hemostasis as well as in the pathophysiology of thrombotic disorders. However, in addition to hemostasis, platelets are involved in a variety of pathophysiological responses including immune responses, inflammation, angiogenesis, tissue regeneration, and cancer metastasis. Recent studies revealed a significant role for platelet-derived microparticles (PMP), in these responses. PMP communicate with, and deliver signals to, other cells, induce signals, and change their phenotype during inflammation, angiogenesis, and tumor metastasis. The current report describes the recent development in this field with a focus on the role of platelets and PMP in all of the above responses.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available