Journal
FRONTIERS IN BIOSCIENCE-LANDMARK
Volume 17, Issue -, Pages 2550-2558Publisher
BIOSCIENCE RESEARCH INST-BRI
DOI: 10.2741/4070
Keywords
Body Mass Index; Cancer; Epidemiology; Gallbladder; Lifestyle Modification; Obesity; Review
Categories
Funding
- General Project Foundation of Science and Technology Department of Liaoning Province [2011225015]
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Obesity has become a global health issue because of its increased morbidity and mortality, and a close association with at least 20 different cancers. Clinical and epidemiological studies have suggested that obesity and overweight are positively related with the risk of GBC. Gallbladder cancer (GBC) is a relatively infrequent but highly lethal neoplasm. Obesity may disturb lipid and endogenous hormones metabolism, affect gallbladder motility, increase the risk of gallstones, and thus plays a role in GBC. Control of obesity through measures such as lifestyle modification, healthy diet, and regular exercise may prove useful in the prevention of GBC.
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