4.5 Article

Biomolecular studies by circular dichroism

Journal

FRONTIERS IN BIOSCIENCE-LANDMARK
Volume 16, Issue -, Pages 61-73

Publisher

FRONTIERS IN BIOSCIENCE INC
DOI: 10.2741/3676

Keywords

Biomolecular; Protein; Peptide; DNA; Biophysical tools; Circular Dichroism; Review

Funding

  1. National Council of Scientific and Technical Research of Argentina (CONICET) [PIP 114-200801-00090]
  2. National Agency for Promotion of Science and Technology (ANPCyT) [PICT-2008-0083]
  3. National University of South [ZQ/024]

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In this review, we shall outline the basic principles of circular dichroism (CD) indicating the types of structural information relevant to the study of biomolecules, such as proteins or DNA. We are mainly interested to show the utility of this technique to study protein-ligand, DNA-ligand and protein-DNA interactions.

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