Journal
FREE RADICAL RESEARCH
Volume 43, Issue 8, Pages 753-760Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10715760903040628
Keywords
Ultra-endurance exercise; Ironman triathlon; DNA damage; apoptosis; total antioxidant capacity
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The major aims of this study were to investigate the effect of an Ironman triathlon on DNA migration in the single cell gel electrophoresis assay, apoptosis and necrosis in the cytokinesis-block micronucleus cytome assay with lymphocytes and on changes of total antioxidant capacity in plasma. Blood samples were taken 2 days (d) before, within 20 min, 1 d, 5 d and 19 d post-race. The level of strand breaks decreased (p0.05) immediately after the race, then increased (p0.01) 1 d post-race and declined (p0.01) until 19 d post-race. Apoptotic and necrotic cells decreased (p0.01) and the total antioxidant status increased (p0.01) immediately after the race. The results indicate that ultra-endurance exercise does not cause prolonged DNA damage in well-trained male athletes.
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