Journal
FORENSIC SCIENCE INTERNATIONAL-GENETICS
Volume 6, Issue 4, Pages 437-446Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.fsigen.2011.09.002
Keywords
Y-STR; Yfiler; Tibet; U-Tsang; Amdo; Kham
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Funding
- Florida International University
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In the present study, we analyzed 17 Y-STR loci in 350 Tibetan males from three culturally defined regions of historical Tibet: Amdo (88), Kham (109) and U-Tsang (153). A total of 299 haplotypes were observed, 272 (90.9%) of which were unique. Only one Y-STR profile is shared across the three Tibetan groups and, incidentally, is also the most frequent haplotype (4.0%), represented by two, five and seven individuals from U-Tsang, Kham and Amdo, respectively. The overall haplotype diversity for the three Tibetan populations at 17 Y-STR loci was 0.9978 and the corresponding values for the extended (11-loci) and minimal (9-loci) haplotypes were 0.9935 and 0.9909, respectively. Both neighbor-joining and Rst pairwise analyses suggest a close genetic relationship between the Amdo and Kham populations, while U-Tsang is genetically distinct from the aforementioned groups. The results demonstrate that the 17 Y-STR loci analyzed are highly polymorphic in all three Tibetan populations examined and hence useful for forensic cases, paternity testing and population genetic studies. (C) 2011 Elsevier Ireland Ltd. All rights reserved.
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