4.5 Article

Haplotype diversity of 17 Y-chromosomal STR loci in the Bangladeshi population

Journal

FORENSIC SCIENCE INTERNATIONAL-GENETICS
Volume 4, Issue 2, Pages E59-E60

Publisher

ELSEVIER IRELAND LTD
DOI: 10.1016/j.fsigen.2009.05.005

Keywords

DNA; STR; Bangladeshi; Y chromosome; Haplotype; Variants

Funding

  1. Multi-Sectoral Program on Violence Against Women
  2. Ministry of Women and Children Affairs, Government of the People's Republic of Bangladesh
  3. Danish International Development Assistance (DANIDA)

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Haplotype and allele frequencies of 17 Y-chromosomal STR loci were determined in 216 unrelated Bangladeshi males. AmpFlSTR(R) Y-filer(TM) PCR Amplification kit (Applied Biosystems) was used to type the following Y-STR markers: DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385a/b, DYS438, DYS439, DYS437, DYS448, DYS458, DYS456, DYS635, and Y-GATA-H4. A total of 211 haplotypes for the 17 Y-STR markers were detected and, of these, 206 haplotypes were unique. The haplotype diversity was 0.9998, indicating a high potential for differentiating between male individuals in this population. Comparison analysis via Analysis of Molecular Variance (AMOVA) and construction of Neighbor Joining Tree revealed a close association of Bangladeshi population with Indian Gaddi and Southern Indian populations. (C) 2009 Elsevier Ireland Ltd. All rights reserved.

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