Journal
FORENSIC SCIENCE INTERNATIONAL-GENETICS
Volume 4, Issue 1, Pages E23-E24Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.fsigen.2009.01.008
Keywords
Autosomal DNA marker; Brazilian population; Genetic distance; Short tandem repeat; STR
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Funding
- Universidade Estadual do Norte Fluminense Darcy Ribeiro and the Hospital Escola Alvaro Alvim [020]
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Allele frequencies data, paternity and forensic parameters for 15 autosomal short tandem repeat (STR) autosomal markers (D8S1179, D21S11, D7S820, CSF1PO, D5S818, D3S1358, TH01, D13S317, D16S539, D2S1338, TPOX, D19S433, vWA, D18S51, FGA) were determined for a sample of 494 unrelated individuals undergoing kinship analysis and molecular cytogenetic testing from the population of the city of Campos dos Goytacazes, Northern State of Rio de Janeiro, Brazil. The loci with the highest polymorphism information content were D18S51 (0.874), D2S1338 (0.853), FGA (0.852), D21S11 (0.838). The combined power of discrimination and the combined power of exclusion were 0.999999999999999 and 0.999526684, respectively. At the available common loci CSF1PO, TH01, TPOX, vWA, D16S539, D7S820 and D13S317, allele frequencies were compared with population databases from State of Alagoas, State of Amazonas, State of Sao Paulo (Brazilian mulattoes, descendants of Europeans, Africans or Asians), State of Mato Grosso do Sul and State of Rio de Janeiro. No significant distances were observed. The interpopulation genetic distance (Fst coefficients) to the present database, ranged 0.0022 (p = 0.446) (Northern State Rio de Janeiro-State of Sao Paulo European-descendants) to 0.0138 (p = 0.993) (Northern State Rio de Janeiro-State of Sao Paulo Asian- descendants). The Asian-descendants Brazilians are the least admixed. All other groups are admixed as one unique population. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
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