Journal
FORENSIC SCIENCE INTERNATIONAL-GENETICS
Volume 2, Issue 3, Pages E31-E35Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.fsigen.2007.08.016
Keywords
Short tandem repeat; DNA; Y-STR; Mutation rate; DYS19; DYS385a/b; DYS389I; DYS389II; DYS390; DYS391; DYS392; DYS393; DYS437; DYS438; DYS439; DYS448; DYS456; DYS458
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Funding
- National Institute of Justice (NIJ) [2003-IJ-R-029]
- NIST Office of Law Enforcement Standards
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We have examined 389 father/son sample pairs from U.S. Caucasians, African Americans, Hispanics and Asians using the 17 Y-STR loci in the Yfiler (TM) kit and observed a total of 24 differences between father and son. Thirteen mutations resulted in the gain of a repeat in the son and 11 resulted in a loss of a repeat. All samples resulted in single repeat mutations except one sample which contained a two repeat loss at Y-GATA-H4. Furthermore, two different sample pairs were found to have two mutations. An African American sample pair had a mutation at DYS458 and a second at DYS635 and an Asian sample pair had mutations at DYS439 and Y-GATA-H4. (C) 2007 Elsevier Ireland Ltd. All rights reserved.
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