Journal
FORENSIC SCIENCE INTERNATIONAL
Volume 174, Issue 2-3, Pages 182-188Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.forsciint.2007.04.223
Keywords
Y-chromosome; short tandem repeats; European minimal haplotype; Mentype Argus Y-MH PCR amplification kit; SWGDAM; DYS447; DYS449; DYS481; DYS570; DYS576; population study
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The haplotype discrimination capacity of the 9 Y-chromosomal short tandem repeat (Y-STR) loci comprising the so called minimal haplotype together with additional 26 recently described single-copy Y-STRs was evaluated within 391 males from Germany, The Netherlands, and Turkey. The aim of this study was to identify the minimum number of Y-STRs needed in addition to the recommended 9 minimal haplotype loci or the 11 SWGDAM loci for individualizing male lineages. Highest gene diversities were shown for DYS385 loci, DYS449, DYS481, DYS570, DYS447, DYS576, DYS389-II, and DYS390 (D = 0.7518-0.8746). The five Y-STRs DYS447, DYS449, DYS481, DYS570, and DYS576 comprised the smallest set of loci in addition to the previously recommended standard Y-STRs leading to the individualization of all males from each single population group. Complete resolution of the pooled population was achieved by the additional genotyping of two further loci, DYS446 or DYS505 and DYF406S1 or DYS522. (C) 2007 Elsevier Ireland Ltd. All rights reserved.
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