Journal
FOOD HYDROCOLLOIDS
Volume 42, Issue -, Pages 373-377Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.foodhyd.2014.05.001
Keywords
Gellan; Poly (vinyl alcohol); Tissue regeneration; Phase separation; Soft tissue; Mechanical properties
Categories
Funding
- Engineering and Physical Sciences Research Council [EP/K502984/1]
- Advantage West Midlands (AWM)
- European Regional Development Fund (ERDF)
- Engineering and Physical Sciences Research Council [1311131] Funding Source: researchfish
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The aim of this research was to control the mechanical properties of gellan through the addition of a secondary polymer network, for use as an alternative to current tissue regeneration techniques. Cartilage and skin are complex structures, and a complex structure would therefore be required in order to closely mimic their mechanical properties. In this research, the gellan gels were strengthened through the addition of Poly (vinyl alcohol) (PVA), as the secondary polymer. Compressive strength and compressive stiffness were both increased with the addition on PVA, until 10-15% (w/w). This research has shown that gellan and PVA are phase separated, and the decrease on mechanical strength and stiffness is strongly affected by the polymer overlap concentration, occurring at 14% (w/w). (C) 2014 The Authors. Published by Elsevier Ltd.
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