Journal
FOOD HYDROCOLLOIDS
Volume 42, Issue -, Pages 275-279Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.foodhyd.2014.03.008
Keywords
Brown seaweeds; Anti-bacterial activities; Inhibition zone
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With increasing in emergence of resistance pathogenic microorganisms to majority of antibiotics, there is an urgent and continuous need for exploring and developing cheaper and effective plant based drugs with better bioactive potential and least side effects. Bioactive extracts from four species of brown seaweeds (Sargassum plagyophillum, Sargassum flavellum, Padina australis and Sargassum binderi) of Malaysia origin were tested in vitro for their anti-bacterial activities against gram positive bacteria (Bacillus subtilis and Staphylococcus aureus) and gram negative bacteria (Pseudomonas aeruginosa and Escherichia coli). Four solvents (methanol, acetone, ethyl acetate and chloroform) were used during the preliminary screening stage to obtain crude extracts. None of the crude extracts displayed antimicrobial activity against the gram negative bacteria while the gram positive bacteria were inhibited. Methanol extract of S. plagyophillum was the best in terms of yield (4.72%) and antimicrobial activity with inhibition zone of 12 mm against B. subtilis. Chloroform fraction gave highest inhibition zone of 17 mm against B. subtilis. Hence, the result from this work showed that S. plagyophillum has the potential for antimicrobial drug production. (C) 2014 Elsevier Ltd. All rights reserved.
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