Journal
JOURNAL OF THE SERBIAN CHEMICAL SOCIETY
Volume 80, Issue 6, Pages 819-826Publisher
SERBIAN CHEMICAL SOC
DOI: 10.2298/JSC141225017M
Keywords
natural zeolite; multidrug resistance; polymers; poly(vinyl chloride); amino acids
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Funding
- Ministry of Education, Science and Technological Development of the Republic of Serbia [172018]
- Ministry of Science, Education and Sports of the Republic of Croatia [1191155-1203]
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The multidrug-resistant bacteria Acinetobacter baumannii cause serious hospital infections. Commercial poly(vinyl chloride) (PVC) used for endotracheal tubes was modified in order to obtain a composite with an antibacterial effect towards a clinical isolate of A. baumannii ST145. The composites were prepared by addition of different amounts of copper-containing zeolite tuff (CuZ) and by successive impregnation with D-tyrosine (D-Tyr) solution. The composites that were obtained by addition of CuZ (CuZ PVC) only did not exhibit an antibacterial effect. The impregnation of the CuZ PVC by D-Tyr resulted in an antibacterial effect which was explained by a synergistic effect of CuZ and D-Tyr. Rheological tests confirmed that the modification of PVC by CuZ does not affect its processability and reformability.
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