Journal
FOOD CONTROL
Volume 31, Issue 2, Pages 331-336Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.foodcont.2012.10.030
Keywords
Aflatoxin B-1; Ozone; UPLC Q-TOF MS; Degradation products; Toxicity
Categories
Funding
- Special Fund for Agro-Scientific Research in the Public Interest of PR China [201203037, 200903043-02]
- National Natural Science Foundation of PR China [31171785, 31101383, 31201381]
Ask authors/readers for more resources
Earlier researches showed that aflatoxin B-1 (AFB(1)) can be effectively degraded using ozonation in the aqueous systems. However, the degradation products have not been identified until today. In this article, the degradation products of AFB(1) were analyzed using ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometers (UPLC Q-TOF MS). Under our experimental conditions, six key degradation product structures and possible paths for generating fragment ions were proposed. The proposals were based on the low mass error, high match rate in degradation product speculation, and possible molecular formulas that could be obtained using UPLC Q-TOF MS. UPLC revealed the existence of degradation products, whereas Q-TOF MS exposed the structures of the fragment ions for AFB(1) and its degradation products. Due to the conjugate addition reaction on the double bond of the terminal furan ring for AFB(1), the toxicity of the degradation products was significantly decreased compared with that of AFB(1) through the toxicity analysis of the degradation products according to the structure-activity relationship. The results showed that aqueous ozone treatment was an effective method for degrading AFB(1). (c) 2012 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available