4.7 Article

Colorimetric sensor based on dual-functional gold nanoparticles: Analyte-recognition and peroxidase-like activity

Journal

FOOD CHEMISTRY
Volume 147, Issue -, Pages 257-261

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2013.09.151

Keywords

Colorimetric sensor; Gold nanoparticles; Enzyme mimics; Signal amplification; Melamine; Infant formula

Funding

  1. National Natural Science Foundation of China [21175023]
  2. Program for New Century Excellent Talents in University [NCET-12-0618]
  3. Natural Science Foundation of Fujian Province [2011J01034, 2012106019]
  4. Science and Technology Planning Project of Fujian Province [2011Y0030]
  5. Program for New Century Excellent Talents in Fujian Province University [JA11102]

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A novel colorimetric sensor based on the interaction ability with specific analytes and peroxidase-like activity of gold nanoparticles was established in this work. Combining the high-affinity binding between bare gold nanoparticles and melamine with signal amplification procedure based on the catalytic activity of gold nanoparticles for oxidation of TMB, melamine with the concentration as low as 0.02 mg/L can be easily distinguished by naked-eye observation. Such system can be adapted through carefully-controlled surface modifications of gold nanoparticles for determination of other targets. (C) 2013 Elsevier Ltd. All rights reserved.

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