Journal
FOOD CHEMISTRY
Volume 141, Issue 3, Pages 2501-2506Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2013.05.055
Keywords
Lavandula pedunculata subsp lusitanica; Essential oil; Phenolic compounds; Antioxidants; Alzheimer's disease; Anti-cholinesterases
Funding
- Portuguese Science and Technology Foundation (FCT) [SFRH/BD/63505/2009, SFRH/BPD/31534/2006, SFRH/BD/69951/2010]
- FCT [PEst-C/EQB/LA0006/2011]
- Fundação para a Ciência e a Tecnologia [SFRH/BD/63505/2009] Funding Source: FCT
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We investigated the metabolic profile and biological activities of the essential oil and polar extracts of Lavandula pedunculata subsp. lusitanica (Chaytor) Franco collected in south Portugal. Gas chromatography-mass spectrometry (GC-MS) analysis revealed that oxygen-containing monoterpenes was the principal group of compounds identified in the essential oil. Camphor (40.6%) and fenchone (38.0%) were found as the major constituents. High-performance liquid chromatography with diode array detection (HPLC-DAD) analysis allowed the identification of hydroxycinnamic acids (3-O-caffeoylquinic, 4-O-caffeoylquinic, 5-O-caffeoylquinic and rosmarinic acids) and flavones (luteolin and apigenin) in the polar extracts, with rosmarinic acid being the main compound in most of them. The bioactive compounds from L. pedunculata polar extracts were the most efficient free-radical scavengers, Fe2+ chelators and inhibitors of malondialdehyde production, while the essential oil was the most active against acetylcholinesterase. Our results reveal that the subspecies of L pedunculata studied is a potential source of active metabolites with a positive effect on human health. (C) 2013 Elsevier Ltd. All rights reserved.
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