Journal
FOOD CHEMISTRY
Volume 123, Issue 2, Pages 472-476Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2010.05.033
Keywords
Feruloyl oligosaccharides; Plasma antioxidant activity; Wheat bran
Funding
- Funding Project for Academic Human Resources Development in Institutions of Higher Learning
- Jurisdiction of Beijing Municipality
- General Project of Beijing Municipal Education Commission [KM200910011002]
- Beijing Nova Program [2008B07]
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Wheat bran feruloyl oligosaccharides (FOs) possess in vitro antioxidative potential. The aim of this paper is to investigate the protective effect of FOs against oxidative stress in rat plasma. The levels of oxidative stress markers (oxidised glutathione and malondialdehyde) and the activities of antioxidant enzymes (superoxide dismutase, catalase and glutathione peroxidase) in plasma from rats fed with a standard diet supplemented with 1% FOs were evaluated. The anti-radical capacity of rat plasma after ingestion of 0.5 mg FOs was measured using AAPH as the free radical inducer. Compared to the control group, the antioxidant enzyme activity was higher in plasma from rats fed with FOs, and oxidised glutathione and malondialdehyde levels were lower. Plasmas of rats after ingestion of FOs were more resistant to AAPH-induced hemolysis than was the control group (P < 0.01). These results suggest that FOs enhance the level of antioxidative activity in rat plasma in vivo. (C) 2010 Elsevier Ltd. All rights reserved.
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