4.1 Article

Folate and vitamin B-12 metabolism: Overview and interaction with riboflavin, vitamin B-6, and polymorphisms

Journal

FOOD AND NUTRITION BULLETIN
Volume 29, Issue 2, Pages S5-S16

Publisher

SAGE PUBLICATIONS INC
DOI: 10.1177/15648265080292S103

Keywords

folate; homocysteine; megaloblastic anemia; methionine synthase; MTHFR; neural tube defects; one-carbon metabolism; polymorphisms; riboflavin; vitamin B-12

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This paper provides a general review on folate and vitamin B-12 nutrition and metabolism and the metabolic interrelationship between these vitamins. The effects of some common polymorphisms in folate and vitamin B-12 genes and the influence of vitamin B-6 and riboflavin status on folate and vitamin B-12 metabolism are also discussed.

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