Journal
FOOD AND CHEMICAL TOXICOLOGY
Volume 50, Issue -, Pages S486-S490Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.fct.2012.02.088
Keywords
Fragrance; Review
Categories
Funding
- Research Institute for Fragrance Materials
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A toxicologic and dermatologic review of benzyl propionate when used as a fragrance ingredient is presented. Benzyl propionate is a member of the fragrance structural group Aryl Alkyl Alcohol Simple Acid Esters (AAASAE). The AAASAE fragrance ingredients are prepared by reacting an aryl alkyl alcohol with a simple carboxylic acid (a chain of 1 to 4 carbons) to generate formate, acetate, propionate, butyrate, isobutyrate and carbonate esters. This review contains a detailed summary of all available toxicology and dermatology papers that are related to this individual fragrance ingredient and is not intended as a stand-alone document. Available data for benzyl propionate were evaluated, then summarized, and includes: physical properties, acute toxicity, skin irritation, skin sensitization, elicitation, toxicokinetics, and genotoxicity data. A safety assessment of the entire AAASAE will be published simultaneously with this document. Please refer to Belsito et al. (2012) for an overall assessment of the safe use of this material and all AAASAE in fragrances. (C) 2012 Elsevier Ltd. All rights reserved.
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