Journal
FOOD AND CHEMICAL TOXICOLOGY
Volume 49, Issue 10, Pages 2667-2669Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.fct.2011.07.018
Keywords
Endogenous allergens; Transgenic crops; Regulation; Safety
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The safety assessment for transgenic food crops currently includes an evaluation of the endogenous allergy potential (via serum IgE screening) when the non-transgenic counterpart is a commonly allergenic food. The value of this analysis in the safety assessment of transgenic crops, especially with reference to recent requests to quantify individual allergen concentrations in raw commodities, is examined. We conclude that the likelihood of upregulating an endogenous allergen due to transgenesis is no greater than from traditional breeding which has a history of safety and is largely unregulated. The potential consequences of upregulating an endogenous allergen are also unclear. (C) 2011 Elsevier Ltd. All rights reserved.
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