Journal
FOOD AND CHEMICAL TOXICOLOGY
Volume 48, Issue 7, Pages 1950-1956Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.fct.2010.04.042
Keywords
Food colorant; Food preservative; Neopterin; Indoleamine 2,3-dioxygenase (IDO); Immunomodulation
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Food preservatives sodium benzoate and propionic acid and colorant curcumin are demonstrated to suppress in a dose-dependent manner Th1-type immune response in human peripheral blood mononuclear cells (PBMC) in vitro. Results show an anti-inflammatory property of compounds which however could shift the Th1-Th2-type immune balance towards Th2-type immunity. (C) 2010 Elsevier Ltd. All rights reserved.
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