Journal
JOURNAL OF THE NEUROLOGICAL SCIENCES
Volume 358, Issue 1-2, Pages 417-418Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jns.2015.08.018
Keywords
Vitamin D deficiency; African-Americans; Caucasians; Databases; Big data; Multiple sclerosis; Vitamin D supplementation
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Maintaining adequate levels of vitamin D may have a protective effect and lower the risk of multiple sclerosis (MS). For patients with MS, maintaining an adequate level of vitamin D level is probably associated with lessening of the frequency and severity of their symptoms. However, what remains unclear is whether if this is true across all racial/ethnic backgrounds. In African-Americans (AAs) this effect is not only absent but curiously enough, low levels of vitamin D do not matter since the bioavailability of this molecule in AA subjects is normal. It is this paradox that led to this brief report and we suggest more research and database construction based on race/ethnicity be done, as a first step to understand the biological mechanisms that confer or negate the effect of vitamin D levels in MS. (C) 2015 Elsevier B.V. All rights reserved.
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